Synapse相关论文
Can Hybrid Synapse be Formed between Rat Spinal Motor Neurons and Major Pelvic Ganglion Neurons in v
The purpose of this study is to determine whether synapses can be formed between spinal motor neurons (SMNs)and major pe......
Constraint-induced movement therapy enhances AMPA receptor-dependent synaptic plasticity in the ipsi
Constraint-induced movement therapy (CIMT) can promote the recovery of motor function in injured upper limbs following s......
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction and comm......
Circular HDAC9/microRNA-138/Sirtuin-1 Pathway Mediates Synaptic and Amyloid Precursor Protein Proces
Synaptic dysfunction and abnormal processing of amyloid precursor protein (APP) are early pathological features in Alzhe......
Various recent studies showed that postsynaptic density(PSD)scaffold proteins Shank involved in autism,schizophrenia and......
The neuromuscular junction(NMJ)is a peripheral synapse between motor neurons and skeletal muscle fibers....
Activation of medullary a1A-adrenoceptors increases airway vagal tone via enhanced excitatory inputs
In mammals including the human beings,the neural control of airway smooth muscles is dominated by medullary airway vagal......
Activation of medullary α2-adrenoceptors in vitro does not disinhibit laryngeal motoneurons: failure
The preganglionic recurrent laryngeal motoneurons (PRLMs) dominate the neural control of almost all the intrinsic laryng......
Corticotropin-releasing factor presynaptically attenuated the spontaneous glutaminergic and GABAergi
Corticotrophin-releasing factor(CRF)has a central role in physiological stress.Studies suggest that CRF participates in ......
The role of synaptic-and extrasynaptic NMDA receptors on induction of long-term plasticity in mice h
Long-term Plasticity is an important hypothesis for learning and memory.As disclosed from many experimental data,an acti......
Neurotensinergic augmentation of glutamate release at the perforant path-granule cell synapse in rat
Neurotensin(NT)serves as a neuromodulator in the brain where it is involved in modulating a variety of physiological fun......
Arginine vasopressin regulates the medullary airway vagal preganglionic neurons via the V1a-receptor
The cholinergic pathway or central vagal excitation has been found to be involved in the bronchoconstriction and the inc......
Objective Autism is a severe neurodevelopmental disorder characterized by problems in communication, social skills, and ......
Fast and slow inhibition in the visual thalamus is influenced by allocating GABAA receptors with dif
Cell-type specific differences in the kinetics of inhibitory postsynaptic conductances (IPSCs) impact upon network dynam......
Virus-mediated Knock-down of Dnmt3a and Dnmt1 in the Hippocampus CA1 Impairs Recognition Memories in
Dnmt1 and Dnmt3a are two main DNA Methyltransferases.Recently a lot of reseach indicate that the methylation mediated by......
Chemical inhibition in the central nervous system is primarily mediated by the A type receptors of gammaaminobutyric aci......
Synapses play an important role in neural signaling transmission and sculpting the circuitry of the nervous system.Since......
Corticotropin-Releasing Hormone affects the activity of airway vagal preganglionic neurons via activ
Medullary airway vagal preganglionic neurons(AVPNs)within the external formation of nucleus ambiguus are particularly im......
Glial Derived Thrombospondin-2 Promotes Synaptic Plasticity of Retinal Neurons Following High Pressu
Objective High intraocular pressure(HIOP)is the main pathogenic factor for glaucoma characterized by degeneration of ret......
Activation of medullary α1A-adrenoceptors increases airway vagal tone via enhanced excitatory inputs
In mammals including the human beings, the neural control of airway smooth muscles is dominated by medullary airway vaga......
Activation of medullary α2-adrenoceptors in vitro does not disinhibit laryngeal motoneurons: failure
The preganglionic recurrent laryngeal motoneurons (PRLMs) dominate the neural control of almost allthe intrinsic larynge......
Objective TO investigate the effects of Tao Xin Fang on the learning and memory ability,and the synapse structure and ne......
Lack of a functional TREM2-DAP12 signaling pathway causes early onset cognitive dementia in humans evident by the third ......
Homeostatic synaptic plasticity adjusts neuronal excitability and network activity when global activity perturbation is ......
At mammalian CNS,direct electrical recordings of axons and axon terminals are technically difficult and the knowledge of......
Synaptic loss in the brain correlates well with disease severity in Alzheimer disease (AD).Deficits in brain-derived neu......
ASIC1a channels contribute to dendritic spine development of striatal medium spiny neurons (MSNs) an
Acid-sensing ion channel la (ASIC1a) is widely expressed in nervous systems, contributing to synaptic activity, learning......
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随着肿瘤学和神经科学的发展，其交叉学科——癌症-神经科学也在近年来引起学者们的广泛关注。人们逐渐认识到神经元参与肿瘤微环境......
DL0410 ameliorates cognitive disorder in SAMP8 mice by promoting mitochondrial dynamics and the NMDA
Alzheimer’s disease (AD) is a worldwide problem and there are no effective drugs for AD treatment. Previous studies sho......
Cells are the fundamental unit of life,and communication between cells by release of specific chemical messengers pl......
The synapse of human brain neurons is not only the transmission channel of information,but also the basic unit of human ......
Autism spectrum disorder(ASD)is a neuronal developmental disorder that is characterized by de⁃fects both in social inte......
Disruption of the autism-related gene Pak1 causes stereocilia disorganization,hair cell loss,and dea
Several clinical studies have reported that hearing loss is correlated with autism in children.However,little is known a......
触处的发展是在神经生物学的一个重要问题。我们采用 patchclamp 技术记录 myoballs inXenopus 房间文化的 MEPC 和 EPC。EPC/MEPC......
Polybrominated diphenyl ether (PBDE) is a persistently environmental pollutant ubiquitously found in wildlife and humans......
Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons......
目的 观察幼年应激对成年大鼠应激敏感性的影响及神经机制.方法 将60只雄性SD大鼠随机分为应激组(30只)和非应激组(30)只,应激方式......
Synaptic and blood-brain barrier structural changes in a rat epilepsy model induced by coriaria lact
BACKGROUND: Structural and functional synaptic changes, as well as blood-brain barrier (BBB) changes, affect the micro-e......
Transplantation of activated transgenic Schwann cells or a fetal spinal cord cell suspension has been widely used to tre......
A mathematical model of synaptotagmin 7 revealing functional importance of short-term synaptic plast
Synaptotagmin 7 (Syt7), a presynaptic calcium sensor, has a significant role in the facilitation in short-term synaptic ......
Double Labeling Immunoelectron Microscopic Study on the Synaptic Connections between Glutamic Acid N
In order to explore the roles of different neurotransmitters in epileptic pathogenesis,the synaptic connections between ......
目的：探讨柿叶黄酮类提取物（FLDK）对 APP／PS1小鼠认知水平、突触结构及突触相关蛋白表达的影响。方法20只4月龄 APP／PS1小鼠，随机分为阿......
Myoclonus dystonia syndrome (MDS) is an inherited movement disorder,and most MDS-related mutations have so far been foun......
BACKGROUND: Changes in synaptic plasticity might underlie senile dementia, and might be the neurobiological basis for le......
Double Labeling Immunoelectron Microscopic Study on the Synaptic Connections between Glutamic Acid N
In order to explore the roles of different neurotransmitters in epileptic pathogenesis,the synaptic connections between ......
目的 探讨神经营养素家族蛋白[包括脑源性神经营养因子(BDNF),神经生长因子(NGF),神经营养素-3(NT-3)]是否参与星形胶质细胞条件培......
Synaptic and blood-brain barrier structural changes in a rat epilepsy model induced by coriaria lact
BACKGROUND: Structural and functional synaptic changes, as well as blood-brain barrier (BBB) changes, affect the micro-e......
Integrating Various Neural Features Based on Mechanism of Intricate Balance and Ongoing Activity: Un
In recent decades, brain science has been enriched from both empirical and computational approaches. Interesting emergin......
目的:观察慢性低灌注3个月大鼠空间学习、记忆能力的变化及17β-雌二醇(E2)的长期保护作用,揭示血管性痴呆进行性病变的分子机制.......
